BEGIN:VCALENDAR
VERSION:2.0
PRODID:Linklings LLC
BEGIN:VTIMEZONE
TZID:Europe/Stockholm
X-LIC-LOCATION:Europe/Stockholm
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:19700308T020000
RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=-1SU
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:19701101T020000
RRULE:FREQ=YEARLY;BYMONTH=10;BYDAY=-1SU
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTAMP:20210916T132448Z
LOCATION:Henry Dunant
DTSTART;TZID=Europe/Stockholm:20210705T160000
DTEND;TZID=Europe/Stockholm:20210705T163000
UID:submissions.pasc-conference.org_PASC21_sess121_msa103@linklings.com
SUMMARY:Lattice-Boltzmann Mesoscopic Fibrinolysis
DESCRIPTION:Minisymposium\n\nLattice-Boltzmann Mesoscopic Fibrinolysis\n\n
 Petkantchin, Raynaud, Chopard\n\nIschemic stroke disease is the 1st cause 
 of disability and 3rd cause of death in civilized countries. Treatment opt
 ions are thrombolysis and thrombectomy. The latter consists in the mechani
 cal removal of the blood clot, through surgery. The former, consists in th
 e chemical breakdown of the clot, by injecting a fibrin-lysing product, co
 mmonly called tPA. However, treatment success rates are still very low: on
 ly 30% of the patients will have fully recovered 3 months after treatment.
  Our goal is to better understand the thrombolysis process in patients, us
 ing numerical modeling and HPC simulations. We consider 3D Lattice Boltzma
 nn flow simulations on top of which we add the processes of tPA transport 
 and fibrin dissolution. Blood flow is computed in patient-specific arterie
 s, with patient-specific blood clots acting as porous media whose porosity
  increases as the lysis takes place. We propose a local permeability model
  which allows us to deal with heterogeneous clot composition, as observed 
 in patients. The permeability factor and lysis properties can be specified
  at each point of the clot, and yield a realistic global behavior, even du
 ring the lysis regime.\n\nDomain: CS and Math, Chemistry and Materials, Ph
 ysics, Life Sciences, Engineering
END:VEVENT
END:VCALENDAR